PPT Slide

Milestones (keynote papers) in the development of tenofovir

C.C. Tsai, K.E. Follis, A. Sabo, T.W. Beck, R.F. Grant, N. Bischofberger, R.E. Benveniste

& R. Black.

Prevention of SIV infection in macaques by (R)-9-(2-phosphonylmethoxypropyl)adenine.

Science 270, 1197-1199 (1995).

R.A. Otten, D.K. Smith, D.R. Adams, J.K. Pullium, E. Jackson, C.N. Kim, H. Jaffe,

R. Janssen, S. Butera & T.M. Folks.

Efficacy of postexposure prophylaxis after intravaginal exposure of pig-tailed macaques

to a human-derived retrovirus (human immunodeficiency virus type 2).

J. Virol. 74, 9771-9775 (2000).

K.K. Van Rompay, M.B. McChesney, N.L. Aguirre, K.A. Schmidt, N. Bischofberger &

M.L. Marthas.

Two low doses of tenofovir protect newborn macaques against oral simian immuno-

deficiency virus infection.

J. Infect. Dis. 184, 429-438 (2001).