PPT Slide

Das et al., J. Virol. 75: 4771-4779 (2001)

Interaction of ADVDP (adefovir diphosphate) with YMDD region

of HBV DNA polymerase

Both wild-type (left) and Met552Val+Leu528Met mutant (right) HBV DNA polymerase appear to have no steric

conflict with a docked ADVDP.