PPT Slide

Hypermutable phenotype

• Screening for hypermutable phenotype
  • 91 strains in 25 CF patients (various phenotypes)
  • 71 strains in non CF patients [isolates from broncho-pulmonary secretions (n=51) and blood (n=20)]
  • Determination of mutation frequencies for rifampin (100 mg/L)
  • Inoculum: 108; in triplicate
  • Control with streptomycin for hypermutable strains

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