Spectrum of Activity
Spectrum of activity includes Candida albicans, non-albicans Candida spp., and Aspergillus spp.
- fungicidal for Candida spp.
- ‘fungistatic’ against Aspergillus spp.
MIC and in vitro/vivo data
Efficacy proven in animal models
No cross-resistance to Candida spp. with intrinsic or acquired resistance to fluconazole, amphotericin B, or flucytosine
No activity against Cryptococcus neoformans
Activity against other fungi less well defined