Ertapenem: Relation structure-activité
N
H3C
O
O
H
CH3
S
N
H2
H
N
O
O
O
O
O
Trans hydroxyethyl
1?-methyl
Groupement benzoate: modifie charge ? taux élevé de laision aux protéines, t1/2 augmenté (? 4h), ? permet dosage “once-a-day”
Na
+
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