Analysis of ciprofloxacin activity against S. pneumoniae after 10 years use in US
5,640 isolates collected from 377 geographically distributed US hospitals
collected over 1997-98 respiratory season
0.3% of isolates had cipro MICs of ?4 ?g/ml
resistance strains significantly associated with:
- ᡸ years of age
- respiratory source
- penicillin resistance