PPT Slide
Antiviral activity of PMEA first mentioned in 1986
Licensed for clinical use for the treatment of HBV infections
(chronic hepatitis B) in September 2002.
E. De Clercq, A. Holư, I. Rosenberg, T. Sakuma, J. Balzarini &
A novel selective broad-spectrum anti-DNA virus agent.
Nature 323, 464-467 (1986).