PPT Slide

Guerhier et al., Antimicrob. Agents Chemother., 45: 1065-1077 (2001)

WHV endogenous DNA polymerase activity in serum of woodchucks chronically

infected with WHV

Short-term ?-L-Fd4C administration induces a transient but more potent antiviral effect than 3TC. ?-L-Fd4C and

3TC were administered intraperitoneally at 1 mg/kg/day for 15 consecutive days to four woodchucks (per group)

chronically infected with WHV. ?, controls; ?, ?-L-Fd4C; ?, 3TC.