de Louvain (UCL-Bruxelles)
Louvain Drug Research Institute (Department of Pharmaceutical Sciences)
Centre for Clinical Pharmacy
|Site en francais | In het Nederlands|
Clinical Pharmacy is a pharmaceutical
activity centered on the patient. Its primary objective is to ensure the most
appropriate and safe use of medicines. In this activity, the pharmacist uses
his/her knowledge and skills relative to pharmacology, pharmacotherapy and communication
with other health care professionals and patients in order to promote the effective
use of medicines in hospitals and in primary care.
The Centre has been created informally in 2003 to house the Research and Advanced Teaching activities of our University and of its affiliated hospitals in Clinical Pharmacy. It is presently in the process of being formally incorporated in the new structure of the University as part of the "Louvain Drug Research Institute".
Study of the appropriateness of medicines use in selected hospital wards, to demonstrate the value of optimization strategies within the context of Clinical Pharmacy Services.
Current research programs
There are three main ongoing programmes (PhD):
Additional programmes are ongoing through
collaborations with other Universities in Belgium and with the Belgian Health
Care Knowldge Center (KCE).
Research methods used
|Example 1: Appropriateness of use of medicines in elderly inpatients: qualitative study|
|(from Spinewine et al.,British Medical Journal, 2005; 331:935-939 ] )|
2: Impact of a clinical pharmacist providing pharmaceutical
care on a geriatric unit: quantitative study
(from Spinewine et al., unpublished)
3: Impact of a clinical pharmacist on the optimization
of vancomycin administration to patients using continuous infusion
(from Ampe et al. unpublished)
The intervention of the clinical pharmacist was intrumental for (i) applying throughout the hospital a mode of administration (continuous infusion) that minimizes sampling error for therapeutic drug monitoring and is compatible with the PK/PD properties fo the drug (AUC-dependent); (ii) calculating with AUC/MIC ratio will be conductive of success, and thereby establishing the limits of MIC an organism may display while remainijg susceptible to the drug given the serum levels obtained.
Clinical Pharmacy Practice
Clinical pharmacists provide pharmaceutical care from admission to discharge, as illustrated in the figure below.
Education in Clinical Pharmacy
A. In Belgium
Education is organized at the post-graduate level (after the Masters degree of Pharmacist). Two possibilities are open to candidates:
Other educational activities include weekly workshops and/or seminars in clinical pharmacy.
Exchanges between Belgian (UCL) and Canadian (Université de Montréal) professors and researchers are made each year, in order to encourage cooperation and reinforce educational as well as research activities developed by our Center
The Centre provides guidance
and expertise to the University of Pharmacy in Hanoi, Vietnam, for the launching
of Clinical Pharmacy in this country
(through a cooperative programme supported by Wallonie-Bruxelles International)
See details at http://www.facm.ucl.ac.be/advanced-courses.htm
ExpertiseThe Centre has expertise in and may enter in contracted research for
Scientific Staff and contact
Professor A. Spinewine (PharmD,
Master Clin. Pharm. [London], PhD
Tel. +32-81-42.33.18 or +32-2-764.72.36 - <firstname.lastname@example.org>
Professor L. Wilmotte
Tel. +32-2-764.36.34 <email@example.com>
Advisory Board and Associate
(by alphabetic order)
Prof. Y. Glupczynski (Microbiology), Dr J.D. Hecq (Hospital Pharmacy), Prof. Y. Horsmans (Gastroenterology), Prof. M. Lambert (General Internal Medicine), Prof. Ch. Lefebvre (General Internal Medicine), Prof. L. Mallet (Clinical Pharmacy, Université de Montréal, Québec), Prof. C. Swine (Geriatry), Prof. F. Van Bambeke (Pharmacology)