Bibliographic Information
AlCl3-DMF complex as catalyst in the Friedel-Craft reaction. The
reactivity of anhydrides and chlorides of dicarboxylic
acids. Taverne, Thierry; Depreux, Patrick;
Lesieur, Daniel; Henichart, Jean-Pierre; Poupaert, Jacques
H.. Institut de Chimie Pharmaceutique, Faculte de
Pharmacie, Universite de Lille II, Lille,
Fr. Bulletin des Societes Chimiques Belges
(1997), 106(12), 791-801. CODEN: BSCBAG ISSN:
0037-9646. Journal written in English.
CAN 128:230293 AN 1998:130193
CAPLUS
Abstract
This paper reports different examples of Friedel-Crafts acylation of
various substrates with dicarboxylic acid chlorides (phthalic,
isophthalic, and malonyl synthons) in the presence of the AlCl3-DMF
complex as catalyst. When 2(3H)-benzothiazolone reacted with
phthalic anhydride in the presence of the AlCl3-DMF complex as
catalyst, in addn. to the product of 6-substitution,
4-(2-carboxybenzoyl)-2(3H)-benzothiazolone was obtained as a
contaminant. This is the first product ever obtained with a
4-substitution in the acylation of 2(3H)-benzothiazolone.
Indexing -- Section 28-7 (Heterocyclic Compounds (More Than One
Hetero Atom)