Theoretical approach to the destruction or sterilization of drugs in aqueous solution

Catherine Slegers, and Bernard Tilquin

Radiation Physics and Chemistry 72 (2005) 363-365


Abstract

Two novel applications in the radiation processing of aqueous solutions of drugs are the sterilization of injectable drugs and the decontamination of hospital wastewaters by ionizing radiation. The parameters influencing the destruction of the drug in aqueous solutions are studied with a computer simulation program. This theoretical approach has revealed that the dose rate is the most important parameter that can be easily varied in order to optimize the destruction or the protection of the drug.

Keywords: Radiation processing; Radiosterilization; Decontamination; Drugs; Wastewater; Computer simulation