Role of the autonomous nervous system in the cerebral response to a low concentration of intragastric glucose perfusion in mice.

Knauf C., Mokhliss E., Cani P.D., Martinez E., Fioramonti X., Perrin C., Iglesias M.A., Burcelin R.

During the post-prandial period, glucose absorbed in the duodenum is conducted to the liver via the hepatoportal vein. Glucose then enters the systemic circulation to reach the heart, from where it is distributed to other organs. Whole body glucose fluxes are controlled by numerous neuronal, hormonal and metabolic factors in order to maintain a normal glycaemia. Increases of glucose concentration are detected by specialized structures called glucose sensors. These structures are situated in different body locations, such as in the pancreas (beta-cells), in the hepatoportal