Planta Med  2003 Jan;69(1):75-7 

The Vasorelaxant Activity of Marrubenol and Marrubiin from Marrubium vulgare.

El Bardai S, Morel N, Wibo M, Fabre N, Llabres G, Lyoussi B, Quetin-Leclercq J.

Laboratoire de Pharmacognosie, Universite catholique de Louvain, Brussels,
Belgium.

Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro
inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations,
spectroscopic analysis and chemical derivatization revealed the furanic labdane
diterpenes marrubenol and marrubiin as the most active compounds.

PMID: 12567286 [PubMed - in process]